Lesions involving peripheral nerves usually caused by traumatic accidents have a severe incidence in terms of quality of life for patients and could produce motor control deficits and alterations in sensorial functions.

Thanks to regenerative medicine it is possible to operate on patients with injuries in their peripheral nervous system. Progress has been made in this field, for instance, by Tekniker, the Basque technology centre member of the Basque Research and Technology Alliance (BRTA), within the framework of the European NEURIMP project whose highly successful results in preclinical trials on animals have been published in the prestigious North American scientific journal ACS Biomaterials Science and Engineering.

The solution intends to propose an alternative to using autologous implants to treat trauma patients.

As an alternative to these implants, Tekniker researchers have combined state of the art biocompatible and biodegradable materials with scalable manufacturing technologies to develop advanced implants that can recover peripheral nerve functionality.

In addition to coordinating the project, the technology centre has focused its activities on developing integrated technologies in areas of specialisation such as surface engineering and advanced manufacturing to process polymers at a micrometric scale and optimise the tubular structure (made of up microchannels) of implants to mimic native nerve geometry.

The Basque technology centre has also worked with synthetic and natural polymers synthesised by other consortium partners and their combinations to adapt micromanufacturing technologies to the biophysical properties of new materials.

Both the feasibility and effectiveness of Tekniker’s innovative technology have been validated in preclinical trials on animals, specifically with rats, to perform sciatic nerve implant surgery and the results reported were better than those obtained with commercial implants.

The publication of these advances by specialised media acknowledges the top-quality research currently under way at Tekniker and will provide the necessary driving force to develop solutions in the field of regenerative medicine.

This project has received funding from the European Community's Seventh Framework Programme (FP7-NMP-2013-SME-7) under grant agreement no 604450.

Further information HERE.